Http://www.brainshark.com/sial/vu?pi=zGoz71yO3z2elxz0 - The van Deemter equation is important in HPLC.
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Van Deemter equation
Relation in chromatography
The van Deemter equation in chromatography, named for Jan van Deemter, relates the variance per unit length of a separation column to the linear mobile phasevelocity by considering physical, kinetic, and thermodynamic properties of a separation.[1] These properties include pathways within the column, diffusion (axial and longitudinal), and mass transferkinetics between stationary and mobile phases.
In liquid chromatography, the mobile phase velocity is taken as the exit velocity, that is, the ratio of the flow rate in ml/second to the cross-sectional area of the ‘column-exit flow path.’ For a packed column, the cross-sectional area of the column exit flow path is usually taken as times the cross-sectional area of the column.
Alternatively, the linear velocity can be taken as the ratio of the column length to the dead time. If the mobile phase is a gas, then the pressure correction must be applied. The variance per uni